Indeed, totally makes me think of Freezer/Bhu, lol.
I've seen the trailer. Looks nice and more serious―at least in terms of danger assessment―compared to the previous BW movies (Victini's only put the lives of some in risk; Kyurem's only endangered Keldeo & co.)
One thing I've often wondered with many Pokemon movies is how people are often conveniently not around whenever there's danger. Most recently, when Kyurem and its army of Cryogonal chased after Keldeo, no citizen was outside (sure, it was at night, but still) except Ash & co. despite Kyurem et al spewing Ice Beam here and there. It's nice to see that people are finally getting involved in the dangers our main characters are facing that can possibly result in lots of deaths and high casualties. /I'm sick
Also, yeah, I was shocked to see that Mewtwo's VA is female. I thought it was a narrator or someone else, but lines like "just like me, those Genesect are also man-made Pokemon" gave it away. I watched Mewtwo's movies in both Japanese and English dubs and I'm certain he (yes, he!) was voiced by a male VA in both versions...