For me it depends on the language I play in. If I play in English, I like to sit back and turn on auto play while having tea at times, but when I'm playing in Japanese I play manually because I'm a bit slower in general.
The only time I played in Japanese and turned on auto mode was when I was playing a game that was so boring I was desperately trying to keep it going and get to the end while getting distracted with other things so I wouldn't fall asleep. In the end I still ended up too sleepy to continue and decided to drop the game altogether.