It depends on how it's adapted. For example, TMGS has two short minigames, which I believe are per route, but they're not very repetitive, and you have many other things to worry about, so you don't really notice them. JackJeanne is a perfect example of how adapting minigames into a visual novel needs to be well implemented. They force you to play approximately 15 songs per route, and the stats game is tedious because you really only have to fill in one stat; there's no real complexity, and it should even be skippable. There are also dialogues without voice acting that have little or nothing to do with the main story, and simply trying to complete the routes becomes a real ordeal. Psychedelica BB, while not entirely to my liking, had a minigame that appeared once or twice per route, and that was it. It didn't interrupt the experience for me.